Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group
نویسندگان
چکیده
This Policy Review presents the International Myeloma Working Group's clinical practice recommendations for treatment of relapsed and refractory multiple myeloma. Based on results phase 2 3 trials, these are proposed patients with disease who have received one previous line therapy, myeloma two or more lines therapy. These integrate issue drug access in both low-income middle-income countries high-income to help guide real-world thus improve patient outcomes.
منابع مشابه
International Myeloma Working Group recommendations for the treatment of multiple myeloma-related bone disease.
PURPOSE The aim of the International Myeloma Working Group was to develop practice recommendations for the management of multiple myeloma (MM) -related bone disease. METHODOLOGY An interdisciplinary panel of clinical experts on MM and myeloma bone disease developed recommendations based on published data through August 2012. Expert consensus was used to propose additional recommendations in s...
متن کاملTreatment of relapsed and refractory multiple myeloma.
The definition of relapsed and refractory myeloma was straightforward when melphalan-prednisone constituted the mainstay of treatment and high-dose therapy with transplantation was rarely used in myeloma. However, several advances have occurred in the treatment of myeloma over the past decade. Most notably, high-dose therapy and transplantation have become broadly applicable, thalidomide has be...
متن کاملRelapsed and RefRactoRy Multiple MyeloMa
• Objective: To review the management considerations in patients with relapsed and refractory multiple
متن کاملTreatment of Multiple Myeloma
Les traitements classiques de myelome multiple et les schemas differents proposes ont ete mis en revue. La poly chimiotherapie de la maladie avec une com-binaison de cyclophosphamide, B.C.N.U. Alkeran, Perdnisone et Vincristine a donnee une meilleur Resultat ceci surtout dans les formes graves et rapidement progressive de la maladie. D'autres sehemas therapeutiques sont en cours.
متن کامل[Pomalidomide in the treatment of relapsed and refractory multiple myeloma].
Despite improvements in multiple myeloma therapy, the vast majority of patients continue to suffer relapses. Unfortunately, many patients event. develop disease that is refractory to lenalidomide and bortezomib and have few treatment options. Pomalidomide is a potent second-generation immunomodulatory agent with direct antiproliferative, pro-apoptotic, and antiangiogenic effects, as well as mod...
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ژورنال
عنوان ژورنال: Lancet Oncology
سال: 2021
ISSN: ['1474-5488', '1470-2045']
DOI: https://doi.org/10.1016/s1470-2045(20)30756-7